Uribel – clinical Phamacology

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HYOSCIAMIN sulfate is a sulfate that relaxes smooth muscles and thus produces a spasmolytic effect. It is well absorbed from the gastrointestinal tract and rapidly spreads throughout the body tissues. Most of the body’s urine is absorbed within 12 hours, 13% to 50% unchanged. Its biotransformation of the liver. Ligation of his proteins? moderate.

METENAMIN decomposes in acidic Uribel release formaldehyde, which provides bactericidal or bacteriostatic action. It is well absorbed from the gastrointestinal tract. urine without change at some point substances, if the sour urine reaches 70% – 90%. Within 24 hours it is almost completely (90%) from the body; at pH 5, (about 20% is formaldehyde. Binding proteins ? some formaldehyde is due to substances in urine and surrounding tissues. Methenamine is free to spread to the body tissue and fluid, but is not clinically significant as it is not hydrolyzed at pH greater than 6.8.

METHILE BLUE has weak antiseptic properties. It is well absorbed by the gastrointestinal tract and is rapidly reduced to blue leukomethylene, which stabilizes in some form of combination in urine. 75% of the body is unchanged.

FENIL SALICILAT releases salicylate, a mild painkiller for pain.

MONOBASIC sodium PHOSPHATE acidifiers, helps to maintain the necessary for the degradation of Methenamine acid pH in the urine.

Readings and use for Uribel.

Uribel capsules indicated peristalsis dehydration to treat symptoms. Indicated for local aid, symptoms such as inflammation, hypermotility and pain that accompany infections of the lower urinary tract. Indicated for assistance to the urinary tract symptoms caused by diagnostic procedures.

Contraidications

Hypersensitivity to any of the ingredients is possible. The benefits of risk should be carefully considered when the following medical problems exist: heart disease (especially cardiac arrhythmia, heart failure, coronary heart disease and mitral stenosis);  fda.gov obstructive gastrointestinal disease; glaucoma; myasthenia, acute urinary retention may have been produced in chronic uropathy (such as a neck bladder obstacle due to prostatic hypertrophy).

Warnings

Do not exceed the recommended dosage. If a rapid pulse, dizziness or blurred vision occurs, stop using immediately.

Precautions

Uribel - clinical Phamacology

Dmitry Sazonov sensitivity cross and/or related problems

can also be intolerant of this drug to patients intolerant of Belladonna alkaloids or salicylates. Delay in emptying the stomach may complicate the management of a stomach ulcer.

Pregnancy/propagation (FDA pregnancy Category C).

Giosciamine and Methenamine through the placenta. Research on the effects of hyoscyamine and Metenamine on pregnancy and reproduction has not been done in animals or humans. Thus, is it not known whether the Uribel capsules will damage the fetus when a pregnant woman is pregnant or may affect her reproductive potential. Uribel ? capsules should only be given to a pregnant woman if clearly necessary.

Breastfeeding

problems in the human body have not been documented; however, Methenamine and traces of hyoscyamine in mother’s milk. Accordingly, Uribel capsules should be given to the breastfeeding mother with caution and only if clearly necessary.

Prolonged use

there have been no studies to establish the safety of long-term use in the human body. Unknown long-term studies on animals have been carried out to assess carcinogenicity potential.

In children

infants and young children are particularly susceptible to the toxic effects of Belladonna alkaloids.